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Anticancer Activities of Tumor-killing Nanorobots
- Li, Suping, Jiang, Qiao, Ding, Baoquan, Nie, Guangjun
- Trends in biotechnology 2019 v.37 no.6 pp. 573-577
- DNA, antineoplastic activity, blood coagulation, equipment, intravenous injection, neoplasms, therapeutics, thrombin
- Pharmaceutical uses of cancer therapeutics, such as intravenous thrombin to elicit blood coagulation, have been hampered by lack of tumor specificity. Based on rapid progress in DNA origami-based machines capable of transporting molecular payloads, DNA nanorobots have been constructed to specifically deliver therapeutic agents into tumor vessels.