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Direct extraction of astaxanthin from Haematococcus culture using vegetable oils
- Kang, Chang Duk, Sim, Sang Jun
- Biotechnology letters 2008 v.30 no.3 pp. 441-444
- Haematococcus, astaxanthin, culture media, gravity, hydrophobic bonding, vegetable oil
- A green, downstream process using common vegetable oils was used for the direct extraction of astaxanthin from Haematococcus. The process consists of a single integrated unit to extract astaxanthin with subsequent separation of the astaxanthin-containing oil extract. Without a cell harvest process step, the culture broth was directly mixed with the vegetable oils; the astaxanthin inside the cell was extracted into the vegetable oil phase by hydrophobic interactions, with recovery yields of 88% and above. The oil extracts were simply separated from the culture medium containing cell debris by gravity settling only.