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Extraction and Analysis of Xylitol in Sugar-Free Gum Samples by GC-MS with Direct Aqueous Injection
- Rajapaksha, Suranga M., Gerken, Katherine, Archer, Todd, Lathan, Patty, Liyanage, Achala S., Mlsna, Deb, Mlsna, Todd E.
- Journal of Analytical Methods in Chemistry (Online) 2019 v.2019
- consumers (people), dogs, gas chromatography-mass spectrometry, risk assessment, solvents, toxicity, uncertainty, xylitol
- Xylitol, a sugar substitute frequently used in sugar-free gum, is generally considered harmless to humans but it can be extremely toxic to dogs. Dog-owning customers are becoming increasingly aware of the risks associated with xylitol-containing chewing gums. However, there remains some uncertainty if these chewing gums are still dangerous to dogs after they have been partially consumed. In this work, a reliable low-cost analytical method has been developed to quantify the xylitol in sugar-free gum samples. Xylitol was extracted from gum samples using water as a solvent. Extractions were analyzed by GC-MS with direct aqueous injection (DAI). This method was successfully applied to over 120 samples including fresh gum and 5 min, 15 min, and 30 min chewed gum samples.