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Catalytic hydrogenation of α,β-unsaturated carboxylic acid derivatives using copper(i)/N-heterocyclic carbene complexes

Author:
Zimmermann, Birte M., Kobosil, Sarah C. K., Teichert, Johannes F.
Source:
Chemical communications 2019 v.55 no.16 pp. 2293-2296
ISSN:
1364-548X
Subject:
carbenes, carboxylic acids, catalytic activity, copper, hydrogen, hydrogenation, reducing agents
Abstract:
A simple and air-stable copper(i)/N-heterocyclic carbene complex enables the catalytic hydrogenation of enoates and enamides, hitherto unreactive substrates employing homogeneous copper catalysis and H₂ as a terminal reducing agent. This atom economic transformation replaces commonly employed hydrosilanes and can also be carried out in an asymmetric fashion.
Agid:
6312525