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A 6-acetyl-2-naphthol based two-photon fluorescent probe for the selective detection of nitroxyl and imaging in living cells

Author:
Zhang, Pingzhu, Lian, Pingping, Wang, Xiaofen, Li, Xueyan, Wei, Chao, Li, Xiaoliu
Source:
Analytical methods 2019 v.11 no.10 pp. 1299-1303
ISSN:
1759-9679
Subject:
analytical methods, detection limit, fluorescence, fluorescent dyes, image analysis, tissues
Abstract:
A novel two-photon HNO fluorescent probe (TP-HNO) was easily constructed and prepared by combining 6-acetyl-2-naphthol and 2-(diphenylphosphino)-benzoate. TP-HNO exhibited high selectivity (more than 140-fold off–on fluorescence response) and high sensitivity (the detection limit is 78 nM) to HNO in solution. TP-HNO was also applied for two-photon imaging of HNO in living cells and in tissues.
Agid:
6315730