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Photoinduced Transition-Metal-Free Cross-Coupling of Aryl Halides with H-Phosphonates
- Zeng, Huiying, Dou, Qian, Li, Chao-Jun
- Organic letters 2019 v.21 no.5 pp. 1301-1305
- cross-coupling reactions, heterocyclic compounds, moieties, organic halogen compounds, oxides, phosphonates
- Photoinduced transition-metal- and photosensitizer-free cross-coupling of aryl halides (including Ar–Cl, Ar–Br, and Ar–I) with H-phosphonates (including dialkyl phosphonates and diarylphosphine oxides) is reported. Various functional groups were tolerated, including ester, methoxy, dimethoxy, alkyl, phenyl, trifluoromethyl, and heterocyclic compounds. This simple and green strategy provides a practical pathway to synthesize arylphosphine oxides.