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Two new daphnane diterpenes from the roots of Stelleropsis tianschanica
- Zhao, Dan, Shi, Lei-Ling, Guo, Xiong-Fei, Ma, Guo-Xu, Han, Jian-Wei, Yang, Jun-Shan, Xu, Jian-Guo, Zhang, Jing
- Journal of Asian natural products research 2018 v.20 no.12 pp. 1116-1122
- cytotoxicity, diterpenoids, human cell lines, nuclear magnetic resonance spectroscopy, roots, spectral analysis
- Two new daphnane diterpenes named tianchaterpenes A and B were isolated from the roots of Stelleropsis tianschanica. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HRESIMS. Compounds 1 and 2 were evaluated for their cytotoxic activities against HeLa and HCT-8 cell lines. The results showed that all compounds displayed weak cytotoxicities to the HeLa cells and were inactive to the HCT-8 cells.