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Disabling Molecular Recognition through Reversible Mechanical Stoppering
- Soto, Miguel A., MacLachlan, Mark J.
- Organic letters 2019 v.21 no.6 pp. 1744-1748
- chemical reactions, chemical structure, cross reaction, organic compounds
- Mechanical stoppering of a guest molecule prevents its self-assembly with a macrocycle unit, so that both species coexist in a medium but do not recognize each other. The application of a chemical or physical stimulus reverses mechanical stoppering and subsequently enables molecular recognition. This process, which occurs without cross-reactivity and is perceptible at the macroscopic scale, could facilitate programming on/off states in supramolecular materials and molecular devices.