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Self-Assembling Nanoparticles Usher in a New Era of Vaccine Design

Author:
Rappuoli, Rino, Serruto, Davide
Source:
Cell 2019 v.176 no.6 pp. 1245-1247
ISSN:
0092-8674
Subject:
Respiratory syncytial virus, adjuvants, antigens, nanoparticles, vaccines
Abstract:
In this issue, Marcandalli et al. (2019) report a self-assembling nanoparticle bearing an antigen from respiratory syncytial virus. This is the first time the structure, stability, and adjuvanticity of an antigen have been rationally designed at the atomic level and incorporated in one vaccine.
Agid:
6333037