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Engineering Microbes to Produce Polyunsaturated Fatty Acids
- Ji, Xiao-Jun, Huang, He
- Trends in biotechnology 2019 v.37 no.4 pp. 344-346
- human health, metabolism, microorganisms, polyunsaturated fatty acids, synthetic biology
- Polyunsaturated fatty acids (PUFAs) are important for human health. They are traditionally extracted from animals and plants but can be alternatively derived from oleaginous microbes, and engineering microbial metabolism can improve PUFA accumulation. The next frontier is to engineer more efficient PUFA-producing microbes using systems and synthetic biology tools.