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Empirically derived food-based inflammatory potential of the diet, irritable bowel syndrome, and its severity

Author:
Salari-Moghaddam, Asma, Keshteli, Ammar Hassanzadeh, Esmaillzadeh, Ahmad, Adibi, Peyman
Source:
Nutrition 2019 v.63-64 pp. 141-147
ISSN:
0899-9007
Subject:
adults, body mass index, confidence interval, cross-sectional studies, food frequency questionnaires, food groups, food intake, irritable bowel syndrome, men, nutrition risk assessment, odds ratio, women
Abstract:
To our knowledge, no studies have examined the association between the empirically derived food-based dietary inflammatory index (FDII) and irritable bowel syndrome (IBS). The aim of this study was to examine the relationship between the FDII score and IBS in a large sample of Iranian adults.In this cross-sectional study, the dietary intakes of 3363 adults were assessed using a validated dish-based 106-item semi-quantitative food frequency questionnaire (DS-FFQ). The FDII was calculated based on the dietary intakes of food groups derived from DS-FFQ. IBS was assessed using a modified Persian version of the Rome III questionnaire.Participants in the top quintile of the FDII score had a 42% greater risk for IBS than those in the bottom quintile (odds ratio [OR], 1.42; 95% confidence interval [CI], 1.08–1.88). Among women, we observed a significant direct association between the FDII score and IBS after adjustment for potential confounders (OR, 1.44; 95% CI, 1.01–2.04). By body mass index (BMI) status, normal weight subjects (BMI <25 kg/m2) in the top quintile of the FDII score had higher risk for IBS (OR, 1.60; 95% CI, 1.07–2.35) than those in the bottom quintile. These associations were not observed in men or in participants with a BMI ≥25 kg/m2. There was no significant association between the FDII score and IBS subtypes. No significant association between the FDII score and IBS severity was observed.Consumption of a pro-inflammatory diet was associated with increased risk for IBS, especially in women and in individuals with a BMI <25 kg/m2.
Agid:
6346513