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Electroconductive materials as biomimetic platforms for tissue regeneration

Author:
Hosoyama, Katsuhiro, Ahumada, Manuel, Goel, Keshav, Ruel, Marc, Suuronen, Erik J., Alarcon, Emilio I.
Source:
Biotechnology advances 2019 v.37 no.3 pp. 444-458
ISSN:
0734-9750
Subject:
biocompatible materials, biomimetics, cell proliferation, extracellular matrix, muscles, neurons, tissue repair, tissues
Abstract:
In many diseases, tissue regeneration is compromised and/or insufficient to restore tissue/organ function. Therefore, novel regenerative therapies are being developed to enhance resident and transplanted cell proliferation and functional differentiation. Numerous biomaterials engineered to include nanocomponents have emerged as promising candidates to fulfil the need of mimicking the properties of the healthy extracellular matrix. This is particularly important for tissues that require electroconductive support to achieve optimal cellular function, such as muscles and neurons. In this review, we summarize and discuss the current state-of-the-art for electroconductive materials in tissue regeneration, with particular emphasis on materials containing nanocomponents.
Agid:
6348113