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Use of antibacterial toothpaste is associated with higher urinary triclosan concentrations in Asian immigrant women living in Vancouver, Canada

Author:
Dix-Cooper, L., Kosatsky, T.
Source:
The Science of the total environment 2019 v.671 pp. 897-904
ISSN:
0048-9697
Subject:
advertising, body mass index, cosmetics, cutting boards, epidemiological studies, gas chromatography-mass spectrometry, health education, humans, income, teeth, toothpaste, triclosan, urine, women, Canada, China, India, Taiwan
Abstract:
Triclosan is an antibacterial added to consumer products including toothpastes, cosmetics, and plastic cutting boards. Known to disrupt reproductive and hormonal functioning in animals, epidemiological studies indicate that exposure to triclosan may have similar effects on human health.100 women aged 19 to 45 years born in India or China, Hong Kong, and Taiwan new to the Vancouver (Canada) area were recruited in 2015–2016 by word of mouth, public advertisements, and contacts in health and cultural organizations. Participants completed an interview which queried potential sources of triclosan exposure at home and at work and their urine was tested for triclosan by GC–MS. Determinants of urinary triclosan were assessed by Wilcoxon signed-rank test.Triclosan was detected in 62% of urine samples, with an overall GM of 14.5 μg/L (95% CI: 9.7–21.7 μg/L; range: <LOD to 1900 μg/L). Colgate Total® toothpaste users had higher urinary triclosan concentrations (median = 34.0 μg/L) than non-users (median = 2.5 μg/L, ρ < 0.001), a result which was unaffected by adjustment for age, income, BMI, and country of birth. South Asian born women had elevated urinary triclosan compared to East Asian born women.Triclosan exposure via a specific antibacterial toothpaste brand was identified in reproductive age newcomer women in Canada. Health education around brushing teeth well while using lower toothpaste volumes or choosing triclosan-free toothpaste would reduce triclosan exposure.
Agid:
6350774