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Crosslinking catalytic hairpin assembly for high-contrast imaging of multiple mRNAs in living cells

Author:
Huang, Du-Juan, Cao, Ting, Huang, Zhi-Mei, Wu, Zhenkun, Tang, Li-Juan, Jiang, Jian-Hui
Source:
Chemical communications 2019 v.55 no.27 pp. 3899-3902
ISSN:
1364-548X
Subject:
DNA, chemical compounds, chemical reactions, crosslinking, image analysis, messenger RNA
Abstract:
A novel DNA nanotetrad mediated crosslinking catalytic hairpin assembly (CCHA) is reported to generate clumps of cross-linked mesh products for high-contrast and simultaneous imaging of multiple mRNAs in living cells.
Agid:
6353638