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Effects of cadmium exposure on antioxidant enzymes and histological changes in the mud shrimp Austinogebia edulis (Crustacea: Decapoda)

Author:
Das, Shagnika, Tseng, Li-Chun, Chou, Chi, Wang, Lan, Souissi, Sami, Hwang, Jiang-Shiou
Source:
Environmental science and pollution research international 2019 v.26 no.8 pp. 7752-7762
ISSN:
0944-1344
Subject:
Decapoda, antioxidants, cadmium, catalase, enzyme activity, epithelial cells, exposure duration, glycogen, hepatopancreas, histology, lipid peroxidation, muscles, necrosis, oxidative stress, pollutants, shrimp, superoxide dismutase, toxic substances, trace elements
Abstract:
The trace metal cadmium (Cd) is a toxic pollutant known to induce oxidative stress and other sublethal to lethal effects on aquatic organisms. We exposed the marine mud shrimp Austinogebia edulis to Cd concentrations of 0, 0.5, and 5 mg/kg for up to 4 days (24, 48, 72, 96 h). We studied the activity of antioxidant enzymes in the hepatopancreas, gill, and muscle of A. edulis. Antioxidant enzymes (SOD, CAT, and GPx) decreased with increasing Cd concentration and extended exposure time in these three organs of the mud shrimp A. edulis. Increasing Cd concentration led to an increase in ROS and resulted ultimately in membrane lipid peroxidation at higher Cd concentrations. Significant damage of the hepatopancreas of A. edulis was noticed at higher concentrations of Cd, showing damages like the disappearance of epithelial cell boundaries, detachment of cells from the basal lamina, cellular swelling, necrosis, and reduction of glycogen. In conclusion, Cd caused oxidative damage by reducing the activities of antioxidant enzymes and by damaging the tissue structure in major organs of the mud shrimp A. edulis.
Agid:
6360479