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A new tremulane sesquiterpenoid from the fungus Irpex lacteus

Author:
Ding, Jian-Hai, Li, Zheng-Hui, Feng, Tao, Liu, Ji-Kai
Source:
Natural product research 2019 v.33 no.3 pp. 316-320
ISSN:
1478-6427
Subject:
Irpex lacteus, cytotoxicity, enzymes, fungi, isozymes, sesquiterpenoids, spectral analysis
Abstract:
A new tremulane sesquiterpenoid, named irlactam A (1), was isolated from cultures of the fungus Irpex lacteus. The new structure was elucidated by spectroscopic data analysis. The compound was tested for its cytotoxicities on HL-60, SMMC-7721, A-549, MCF-7, and SW480 cells and for its inhibitory activity against isozymes of 11β-hydroxysteroid dehydrogenases (11β-HSD).
Agid:
6361836