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Intracatheter Antifungal Lock Leading to Detrimental Complications

Author:
Puapatanakul, Pongpratch, Lumlertgul, Nuttha, Thongbor, Nisa, Mahamongkholsawat, Jidapa, Kanjanabuch, Talerngsak
Source:
Medical mycology case reports 2018 v.22 pp. 58-60
ISSN:
2211-7539
Subject:
case studies, catheters, dialysis, fungi, mortality, mycoses, patients, peritonitis
Abstract:
As peritoneal dialysis (PD)-related fungal infection is associated with a high mortality rate, the international guidelines recommend immediate removal of the PD catheter in conjunction with at least 2-weeks of antifungal treatment. Some authors have reported successful management of such cases without removing the PD catheter - by instilling an antifungal lock into the retained PD catheter. However, the use of antifungal locks has generally not been well accepted as the standard treatment for fungal peritonitis in PD patients. We report two cases where antifungal lock were performed in PD patients presented with PD-related fungal infection that not only had no effect on abating the infection but also causing paradoxical outcomes.
Agid:
6371443