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Host Genetics, Diet, and Microbiome: The Role of AMY1
- Morán-Ramos, Sofía, Villarreal-Molina, María Teresa, Canizales-Quinteros, Samuel
- Trends in microbiology 2019 v.27 no.6 pp. 473-475
- diet, genes, genetics, microbiome, obesity
- Host gene variants selected by diet adaptation have been associated with the microbiome. Poole et al. (Cell Host Microbe 2019;25;553–564.E7) reported that AMY1 copy number, associated with obesity, also impacts microbiome composition and function. Complex genetics–diet–microbiome interactions and their effect on obesity could eventually translate into personalized nutrition.