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Platinum-Ion-Mediated Self-Assembly of Hairpin Peptides and Synthesis of Platinum Nanostructures

Wang, Jiqian, Zhang, Liyan, Yang, Jingge, Yan, Hongyu, Li, Xiran, Wang, Chengdong, Wang, Dong, Sun, Yawei, Xu, Hai
Langmuir 2019 v.35 no.16 pp. 5617-5625
atomic force microscopy, calorimetry, circular dichroism spectroscopy, histidine, ions, nanofibers, nanorods, peptides, platinum, titration, ultraviolet-visible spectroscopy
Nanostructures and nanomaterials based on peptide self-assembly have attracted tremendous interests due to the functionalities of peptide molecules. Furthermore, the self-assembled peptide nanostructures are also adopted to fabricate nanomaterials and nanodevices. In this work, the intramolecular folding and self-assembly of a β-hairpin peptide CBHH were first studied under the regulation of platinum ion. And then, platinum nanostructures were synthesized through the reduction of platinum ions templated with peptide self-assemblies. The results of circular dichroism spectroscopy, UV–vis spectroscopy, isothermal titration calorimetry, and atomic force microscopy observation showed that platinum ions could promote the conversion of peptide CBHH secondary structure from a random coil to a β-sheet through coordination with histidine residues. Platinum nanostructures including nanorods and one dimensionally aligned nanorods were synthesized through in situ reduction with CBHH self-assembled nanofiber as the templates. And the synthesized platinum nanostructures showed excellent electrocatalytic activities.