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A New Current for the Mitochondrial Permeability Transition

Author:
Bonora, Massimo, Pinton, Paolo
Source:
Trends in biochemical sciences 2019 v.44 no.7 pp. 559-561
ISSN:
0968-0004
Subject:
H+/K+-exchanging ATPase, H-transporting ATP synthase, mitochondria, permeability
Abstract:
Mitochondrial F1/FO ATP synthase participation in the mitochondrial permeability transition pore complex (PTPC) remains controversial. Neginskaya et al. (Cell Rep. 2019;26:11–17) reported an unexpected current with PTPC-like properties in F1/FO ATP synthase C subunit knockout cells that could explain part of the conflictual literature.
Agid:
6380696