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A novel determination of curcumin via Ru@Au nanoparticle decorated nitrogen and sulfur-functionalized reduced graphene oxide nanomaterials

Kotan, Gül, Kardaş, Faruk, Yokuş, Özlem Aktaş, Akyıldırım, Onur, Saral, Hasan, Eren, Tanju, Yola, Mehmet Lütfi, Atar, Necip
Analytical methods 2015 v.8 no.2 pp. 401-408
X-ray diffraction, X-ray photoelectron spectroscopy, curcumin, cysteine, electrochemistry, glassy carbon electrode, graphene oxide, nanocomposites, nanoparticles, nitrogen, scanning electron microscopy, surface area, transmission electron microscopy
We report the synthesis of Ru@Au nanoparticle involved l-cysteine functionalized reduced graphene oxide (rGO) composites (NSrGO/Ru@AuNPs). The nanocomposites were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD). The electrochemical determination of curcumin (CR) has been studied using square wave voltammetry (SWV) on a glassy carbon electrode (GCE) modified with NSrGO/Ru@AuNP composites (NSrGO/Ru@AuNPs/GCE). The effective surface areas (ESAs) of the rGO/GCE and NSrGO/Ru@AuNPs/GCE were calculated to be 347 cm² mg⁻¹ and 1289 cm² mg⁻¹, respectively. These results show that the electrochemical surface area of the NSrGO/Ru@AuNPs/GCE is 3.71 times higher than that of the rGO/GCE. The developed method was also applied successfully for the determination of CR in plasma and the linearity range of CR was 0.001–0.1 nM with a detection limit of 2.0 × 10⁻¹³ M.