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Single point mutation detection in living cancer cells by far-red emitting PNA–FIT probes

Author:
KolevzonContributed equally to this work., N., Hashoul, D., Naik, S., Rubinstein, A., Yavin, E.
Source:
Chemical communications 2016 v.52 no.11 pp. 2405-2407
ISSN:
1364-548X
Subject:
chemical compounds, chemical reactions, messenger RNA, neoplasm cells, peptides, point mutation, single nucleotide polymorphism
Abstract:
Peptide nucleic acid bis-quinoline conjugates are reported as attractive far-red emitting probes that detect mutated mRNA in living cells at SNP resolution.
Agid:
6386058