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A multiple covalent crosslinked soft hydrogel for bioseparation
- Liu, Zhen, Fan, Liuyin, Xiao, Hua, Cao, Chengxi
- Chemical communications 2016 v.52 no.15 pp. 3247-3250
- acrylamides, acrylic acid, chemical reactions, crosslinking, hardness, hydrogels, micropores, polyacrylamide
- A multiple covalent crosslinked gel of poly(acrylamide–acrylic acid) was synthesized by using acrylic acid and acrylamide both as a comonomer and as a covalent crosslinker. The resultant gel showed a high crosslinking degree, tight micropores, but similar softness and marked separation capacity, in contrast to traditional polyacrylamide gels. The gel might serve as a novel matrix in bioseparation.