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A sensitive fluorescent sensor for the detection of endogenous hydroxyl radicals in living cells and bacteria and direct imaging with respect to its ecotoxicity in living zebra fish

Author:
Liu, Fei, Du, Juan, Song, Da, Xu, Meiying, Sun, Guoping
Source:
Chemical communications 2016 v.52 no.25 pp. 4636-4639
ISSN:
1364-548X
Subject:
Danio rerio, bacteria, chemical compounds, chemical reactions, ecotoxicology, fluorescence, fluorescent dyes, hydroxyl radicals, image analysis
Abstract:
We have synthesized a novel fluorescent probe, MPT-Cy2, which shown a high potential for imaging of endogenous ˙OH in living cells and various types of bacteria. In addition, it is an excellent sensor for in vivo imaging of ˙OH generated following treatment with TiO₂NPs in zebra fish.
Agid:
6386867