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Copper-catalyzed radical coupling of 1,3-dicarbonyl compounds with terminal alkenes for the synthesis of tetracarbonyl compounds

Author:
Zhang, Mei-Na, Zhao, Mi-Na, Chen, Ming, Ren, Zhi-Hui, Wang, Yao-Yu, Guan, Zheng-Hui
Source:
Chemical communications 2016 v.52 no.36 pp. 6127-6130
ISSN:
1364-548X
Subject:
alkenes, carbon, chemical bonding, cross-coupling reactions, moieties
Abstract:
A novel and efficient copper-catalyzed radical cross-coupling of 1,3-dicarbonyl compounds with terminal alkenes for the synthesis of tetracarbonyl compounds with a quaternary carbon atom has been developed. Mechanistically, this transformation involves the construction of two C–C bonds and two CO bonds in a one-pot process. The reaction tolerates a wide range of functional groups and proceeds under mild conditions.
Agid:
6387582