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Self-assembled lipoprotein based gold nanoparticles for detection and photothermal disaggregation of β-amyloid aggregates

Author:
Martins, P. A. T., Alsaiari, S., Julfakyan, K., Nie, Z., Khashab, N. M.
Source:
Chemical communications 2017 v.53 no.13 pp. 2102-2105
ISSN:
1364-548X
Subject:
amyloid, chemical reactions, curcumin, fluorescence, gold, lipoproteins, nanogold, nanoparticles
Abstract:
We present a reconstituted lipoprotein-based nanoparticle platform comprising a curcumin fluorescent motif and an NIR responsive gold core. This multifunctional nanosystem is successfully used for aggregation-dependent fluorescence detection and photothermal disassembly of insoluble amyloid aggregates.
Agid:
6390452