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Post-assembly Modification of Phosphine Cages Controls Host–Guest Behavior
- McTernan, Charlie T., Ronson, Tanya K., Nitschke, Jonathan R.
- Journal of the American Chemical Society 2019 v.141 no.17 pp. 6837-6842
- binding capacity, methylation, oxidation, phosphine
- We report the design, synthesis, and post-assembly modification of a new phosphine-paneled supramolecular cage framework, the anion binding ability of which can be modified rationally through selective post-assembly functionalization. The parent phosphine-paneled cage can be modified in situ through oxidation, methylation, or auration. These covalent and coordinative modifications to the exterior of the cage strongly influence the guest-binding properties of the host.