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Authenticating apple cider vinegar’s home remedy claims: antibacterial, antifungal, antiviral properties and cytotoxicity aspect

Author:
Gopal, Judy, Anthonydhason, Vimala, Muthu, Manikandan, Gansukh, Enkhtaivan, Jung, Somang, Chul, Sechul, Iyyakkannu, Sivanesan
Source:
Natural product research 2019 v.33 no.6 pp. 906-910
ISSN:
1478-6427
Subject:
Candida, antibacterial properties, antifungal properties, antioxidant activity, antiviral properties, apple cider, bioactive compounds, cider vinegar, cytotoxicity, traditional medicine, yeasts
Abstract:
These are the days when one would go online first seeking home remedies before seeing a doctor. Apple cider vinegar (ACV) is one such popular yet scientifically under-validated remedy. Our results prove the unequivocal antimicrobial activity of ACV to be true at full strength concentrations. However, the activity cannot be generalised because although strong antibacterial activity was observed at 25% concentrations, in terms of antifungal activity, yeasts, especially Candida were found to be less susceptible. The antimicrobial/antioxidant properties are ascertained to the total phenolic contents of ACV, as confirmed by our characterisation of the bioactive compounds and antioxidant activity. When checking for its cytotoxicity, ACV exhibited toxicity even at concentrations as low as 0.7%. These results indicate that there is no question of generalising the idea of ACV usage, instead more in vitro and in vivo validations are necessary in order to precisely weigh the pros and cons of ACV.
Agid:
6395208