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A NIR phosphorescent osmium(ii) complex as a lysosome tracking reagent and photodynamic therapeutic agent

Author:
Zhang, Pingyu, Wang, Yi, Qiu, Kangqiang, Zhao, Zhiqian, Hu, Rentao, He, Chuanxin, Zhang, Qianling, Chao, Hui
Source:
Chemical communications 2017 v.53 no.91 pp. 12341-12344
ISSN:
1364-548X
Subject:
chemical reactions, image analysis, lysosomes, near-infrared spectroscopy, osmium, phosphorescence, photochemotherapy, phototoxicity, ruthenium
Abstract:
A novel near infrared (NIR) phosphorescent osmium complex (Os1) was developed for lysosome tracking and photodynamic therapy. Owing to its NIR photophysical properties, cellular imaging ability and phototoxicity, it has advantages over its ruthenium analogue (Ru1).
Agid:
6396980