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A NIR phosphorescent osmium(ii) complex as a lysosome tracking reagent and photodynamic therapeutic agent
- Zhang, Pingyu, Wang, Yi, Qiu, Kangqiang, Zhao, Zhiqian, Hu, Rentao, He, Chuanxin, Zhang, Qianling, Chao, Hui
- Chemical communications 2017 v.53 no.91 pp. 12341-12344
- chemical reactions, image analysis, lysosomes, near-infrared spectroscopy, osmium, phosphorescence, photochemotherapy, phototoxicity, ruthenium
- A novel near infrared (NIR) phosphorescent osmium complex (Os1) was developed for lysosome tracking and photodynamic therapy. Owing to its NIR photophysical properties, cellular imaging ability and phototoxicity, it has advantages over its ruthenium analogue (Ru1).