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A review of the components of brown seaweeds as potential candidates in cancer therapy
- Hussain, Ejaz, Wang, Li-Jun, Jiang, Bo, Riaz, Saba, Butt, Ghazala Yasmeen, Shi, Da-Yong
- RSC advances 2016 v.6 no.15 pp. 12592-12610
- Phaeophyceae, antineoplastic activity, antineoplastic agents, aquatic organisms, mechanism of action, neoplasms, therapeutics
- Finding novel anticancer agents is very important for the treatment of cancer, and marine organisms are a valuable source for developing novel agents for clinical application. Therefore, the isolation and identification of novel anticancer components from brown seaweeds and a study of their mode of action is very attractive in current scenarios to assess their potential as an unexplored source for pharmacological applications. This review will reveal the active components of brown algae, together with their antitumor potential toward cancer treatment according to their structure. This should provide useful information for medicinal chemists in their attempts to develop potent anticancer agents.