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Sequential detection of mercury(ii) and thiol-containing amino acids by a fluorescent chemosensor

Author:
You, Ga Rim, Lee, Sun Young, Lee, Jae Jun, Kim, Yong Sung, Kim, Cheal
Source:
RSC advances 2016 v.6 no.5 pp. 4212-4220
ISSN:
2046-2069
Subject:
aqueous solutions, cysteine, fluorescence, glutathione, lead, mercury, silver
Abstract:
A simple fluorescent chemosensor 1 for the sequential detection of Hg²⁺ and cysteine or glutathione was developed by combination of thiosemicarbazide and 8-hydroxyjulolidine-9-carboxaldehyde. Sensor 1 exhibited an ‘ON–OFF’ fluorescence quenching response in the presence of Hg²⁺, which was explained by theoretical calculations. 1 also showed high selectivity in the presence of potential competitors such as Ag⁺ and Pb²⁺. Moreover, the resulting Hg²⁺-2·1 complex acted as an efficient ‘OFF–ON’ sensor for cysteine or glutathione, showing recovery of 2·1 from Hg²⁺-2·1 complex. Therefore, sensor 1 can be employed as a practical fluorescent chemosensor for recognition of Hg²⁺ and thiol-containing amino acids in aqueous solution.
Agid:
6402127