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A novel NBD-based pH “on–off” fluorescent probe equipped with the N-phenylpiperazine group for lysosome imaging

Author:
Ma, Zhao, Lin, Yuxing, Chen, Hui, Du, Lupei, Li, Minyong
Source:
RSC advances 2016 v.6 no.104 pp. 102773-102777
ISSN:
2046-2069
Subject:
fluorescent dyes, image analysis, lysosomes, pH, washing
Abstract:
A novel PET-based fluorescent probe (LN6) targeting to lysosome was found from the synthesized NBD derivatives. This probe was equipped with the novel lysosome-targeted N-phenylpiperazine group, and could be employed to image lysosome and detect its pH change without any washing steps.
Agid:
6410941