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A nano-organo catalyzed route towards the efficient synthesis of benzo[b]pyran derivatives under ultrasonic irradiation

Author:
Nongrum, Ridaphun, Nongthombam, Geetmani Singh, Kharkongor, Mattilang, Star Rani, Jims World, Rahman, Noimur, Kathing, Chingrishon, Myrboh, Bekington, Nongkhlaw, Rishanlang
Source:
RSC advances 2016 v.6 no.110 pp. 108384-108392
ISSN:
2046-2069
Subject:
Fourier transform infrared spectroscopy, X-ray diffraction, adverse effects, catalysts, catalytic activity, chlorpyrifos, energy, energy-dispersive X-ray analysis, gills, magnetism, nanomaterials, pyrans, silica, solvents, synthesis, tadpoles, thiamin, transmission electron microscopy, ultrasonic treatment, ultrasonics
Abstract:
An efficient, one-pot synthesis of benzo[b]pyrans catalyzed by vitamin B₁ functionalized Fe₂O₃@SiO₂ NPs under ultrasonic conditions is reported herein. The nano-organocatalyst was synthesized and characterized by FT-IR, TEM, EDS, powder XRD, etc. Several benzo[b]pyran derivatives were prepared with satisfactory yields and the nanocatalyst was magnetically retrieved and recycled. The salient features of this protocol include convenient work-up procedure, mild reaction conditions, easy catalyst recovery, shorter reaction time and use of green solvents. Ultrasound energy has been meticulously exploited for the synthesis of a nano-organocatalyst as well as for the preparation of several benzo[b]pyran derivatives. The biological activity of the synthesized benzo[b]pyrans were investigated and one of the derivatives was found to demonstrate profound activity in suppressing the side-effects of chlorpyrifos, an insecticide on the morphology of the external gills of the Duttaphrynus melanostictus tadpoles.
Agid:
6413877