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A highly selective “ON–OFF” probe for colorimetric and fluorometric sensing of Cu²⁺ in water

Author:
Naskar, Barnali, Modak, Ritwik, Maiti, Dilip K., Bauzá, Antonio, Frontera, Antonio, Maiti, Pulak Kumar, Mandal, Sukhendu, Goswami, Sanchita
Source:
RSC advances 2017 v.7 no.19 pp. 11312-11321
ISSN:
2046-2069
Subject:
aqueous solutions, colorimetry, copper, fluorescence, fluorometry, image analysis, phenol
Abstract:
We present herein a diformyl phenol based probe, 3-({3-[2,3-dihydroxy-propylimino-methyl]-2-hydroxy-5-methyl-benzylidene}-amino)-propane-1,2-diol (H₅dpm), as a colorimetric and fluorometric chemosensor for selective detection of Cu²⁺ in aqueous solution under physiological conditions. This simple system produces a colorimetric change enabling naked eye detection as well as on–off fluorescence response towards Cu²⁺ in an aqueous medium with a detection limit of 11.2 nM. To further demonstrate the utility of H₅dpm, we next explored the application of H₅dpm for imaging Cu²⁺ in Vero cells. The attractive imaging properties of the H₅dpm probe will open up avenues for molecular imaging and biomedical applications.
Agid:
6414658