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A water-soluble pillararene-based chemosensor for highly selective and sensitive fluorescence detection of l-methionine
- Lin, Qi, Liu, Lu, Zheng, Feng, Mao, Peng-Peng, Liu, Juan, Zhang, You-Ming, Yao, Hong, Wei, Tai-Bao
- RSC advances 2017 v.7 no.55 pp. 34411-34414
- essential amino acids, fluorescence, humans, water solubility
- l-Methionine (l-Met) is an essential amino acid for the human body. The detection of l-Met in water solution is very important. Herein, we report an efficient approach for the fluorescent detection of l-Met with high selectivity and sensitivity in water using a cationic pillararene-based chemosensor (AWP5). When various l-amino acids are added to the AWP5 water solution, only l-Met can induce fluorescence in AWP5 at λₑₘ = 520 nm, showing dramatic enhancement; thus, other amino acid do not interfere in the l-Met recognition process. AWP5 also shows high sensitivity for l-Met in water, with the lowest detection limit of AWP5 for l-Met being 5.46 × 10⁻⁷ mol L⁻¹.