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Synthesis and insecticidal assessment of some innovative heterocycles incorporating a thiadiazole moiety against the cotton leafworm, Spodoptera littoralis
- Fadda, Ahmed A., El Salam, M. Abd, Tawfik, Eman H., Anwar, E. M., Etman, H. A.
- RSC advances 2017 v.7 no.63 pp. 39773-39785
- Spodoptera littoralis, coumarin, imidazoles, moieties, nuclear magnetic resonance spectroscopy, pyridines, pyrroles, thiazoles, thiophene, triazines
- New 2-cyano-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide (1) was utilized as a versatile precursor for the synthesis of various heterocycles, such as pyrrole, pyridine, coumarin, thiazole, pyrido[2′,3′:3,4]pyrazolo[5,1-c]triazine, triazolo[5,1-c]triazine, aminopyrazole, thiophene, 1,3-dithiolane, triazolo[1,5-a]pyrimidine and benzo[d]imidazole derivatives. The newly synthesized compounds were identified by IR, MS, ¹H NMR, ¹³C NMR, DEPT, H–H COSY, HMBC, and HSQC. Representative compounds of the synthesized products were examined and estimated as insecticidal agents against the cotton leafworm, Spodoptera littoralis.