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Treatment of leiomyosarcoma in a tiger (Panthera tigris) with stereotactic radiotherapy

Author:
Boudreaux, Bonnie B., LaRue, Susan M., Rademacher, Nathalie, Neck, Daniel, Grasperge, Britton, Wood, Charles, Baker, David G.
Source:
Veterinary radiology & ultrasound 2019 v.60 no.3 pp. E33
ISSN:
1058-8183
Subject:
Panthera tigris, asymmetry, computed tomography, euthanasia, histopathology, leiomyosarcoma, males, metastasis, nasal cavity, necropsy, radiotherapy
Abstract:
A 10‐year‐old male captive tiger (Panthera tigris) developed right‐sided facial asymmetry and enlargement. Computed tomography revealed a destructive mass of the right maxillary bone with right nasal cavity involvement. Histopathology indicated a spindle cell sarcoma. A single fraction of 22 Gy using stereotactic radiotherapy was prescribed. After treatment, the facial conformation returned to normal and the tiger resumed normal behavior. Diagnostics 4 months later indicated severe metastatic disease. Humane euthanasia and necropsy were performed. This is the first case utilizing stereotactic radiotherapy for the treatment of cancer in a tiger.
Agid:
6423169