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Pt–Ni nanoframes functionalized with carbon dots: an emerging class of bio-nanoplatforms
- Zhao, Yafei, Mu, Lan, Su, Yongxiang, Shi, Liyi, Feng, Xin
- Journal of materials chemistry B 2017 v.5 no.31 pp. 6233-6236
- biocompatibility, carbon quantum dots, cytotoxicity, image analysis, polyethyleneimine, water solubility
- We designed a unique and novel bio-nanoplatform based on Pt–Ni nanoframes (PNnf) functionalized with carbon dots via the EDC/NHS coupling chemistry. The PNnf with open three-dimensional surfaces exhibited excellent water solubility after polyethylenimine modification. Due to low cytotoxicity and excellent biocompatibility, the bio-nanoplatforms were firstly used for MCF-7 cell imaging in vitro. More importantly, the design strategy can be readily generalized to facilitate other multi-functional bio-nanoplatforms for biological and biomedical applications.