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Main content area

Gene polymorphism and risk of idiopathic membranous nephropathy

Author:
Liu, Dongwei, Zhang, Jiahui, Shi, Yan, Liu, Zhangsuo
Source:
Life sciences 2019 v.229 pp. 124-131
ISSN:
0024-3205
Subject:
genes, genetic factors, genetic polymorphism, kidney diseases, pathogenesis, patients, risk
Abstract:
Membranous nephropathy (MN) is the most common primary glomerular disease (PGD) in the world. Currently, MN still lacks specific diagnostic markers and effective treatment strategy. It is speculated that the occurrence of MN is mainly related to environmental and genetic factors. The pathological manifestations of MN patients are diverse, significant differences in response to treatment options, and more reports on young MN patients suggest the importance of genes in the pathogenesis and diagnosis of MN. We will propose a novel perspective on the important role of genes in the pathogenesis of MN baced on the latest research.
Agid:
6428827