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Echinococcus granulosus sensu lato
- Casulli, Adriano, Siles-Lucas, Mar, Tamarozzi, Francesca
- Trends in parasitology 2019
- Canidae, Echinococcus granulosus, adults, cryptic species, definitive hosts, dogs, echinococcosis, eggs, feces, genotype, humans, ingestion, intermediate hosts, larvae, livestock productivity, metacestodes, sheep, taxonomy, zoonoses
- The larval stage of Echinococcus granulosus sensu lato (sl) causes cystic echinococcosis (CE), a neglected and chronic parasitic zoonotic disease infecting estimated over 1 million people worldwide. E. granulosus sl is a species complex with uncertain taxonomic status, including several cryptic species (genotypes): E. granulosus sensu stricto (ss) (G1/3), E. canadensis (G6/7, G8, G10; proposed to be split in E. intermedius (G6/7), E. borealis (G8) and E. canadensis (G10)), E. ortleppi (G4), E. equinus (G5) and E. felidis. Canids, in particular dogs, are definitive hosts for the sexual stage adult worms, while livestock, predominantly sheep, are intermediate hosts for the asexual larval stage metacestodes. Adult worms induce no evident pathology in canids but metacestodes moderately reduce livestock productivity. Humans are accidental dead-end intermediate hosts who are infected by the ingestion of eggs shed in the feces of infected canids.