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Phytochemical profiles, antioxidant and anti-acetylcholinesterasic activities of the leaf extracts of Rhamnus lycioides subsp. oleoides (L.) Jahand. & Maire in different solvents

Benamar, Houari, Rarivoson, Elonge, Tomassini, Lamberto, Frezza, Claudio, Marouf, Abderrazak, Bennaceur, Malika, Nicoletti, Marcello
Natural product research 2019 v.33 no.10 pp. 1456-1462
Rhamnus, acetylcholinesterase, anthraquinones, antioxidants, bioassays, carbohydrates, chemical constituents of plants, enzyme inhibition, ethyl acetate, fatty acids, flavonoids, hexane, leaf extracts, leaves, methanol, methylene chloride, solvents
In this work, the extracts obtained with different solvents from the leaves of Rhamnus lycioides subsp. oleoides (L.) Jahand. & Maire were studied for their phytochemical profile and then for their antioxidant and acetylcholinesterase inhibitory activities. The phytochemical profiles of the extracts in n-hexane, dichloromethane, ethyl acetate, methanol, anthraquinone rich and water, showed the presence of different compounds belonging to several classes of natural products such as flavonoids, anthraquinones, saccharides and fatty acids. For what concerns the biological tests, the ethyl acetate, methanol and anthraquinone rich extracts showed the highest activities in both assays due to the high amount of compounds possessing those properties such as flavonoids and anthraquinones. By consequence, these specific extracts of the species may be considered to be potential sources of natural antioxidant and anti-acetylcholinesterasic compounds.