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Biodegradation of tricresyl phosphate isomers by Brevibacillus brevis: Degradation pathway and metabolic mechanism

Author:
Liu, Ying, Yin, Hua, Wei, Kun, Peng, Hui, Lu, Guining, Dang, Zhi
Source:
Chemosphere 2019 v.232 pp. 195-203
ISSN:
0045-6535
Subject:
Brevibacillus brevis, absorption, acetic acid, adverse effects, biochemical pathways, biodegradation, chlorides, citric acid, flame retardants, ions, isomers, magnesium, malonic acid, metabolism, microorganisms, organophosphorus compounds, oxalic acid, phosphates, potassium, reactive oxygen species, sodium, sulfates
Abstract:
Tricresyl phosphates (TCPs), a typical sort of organophosphate flame retardants, has received extensive concerns due to its potential adverse effects. However, limited information is available on the efficient and safe removal methods of TCPs. In this regard, TCPs were tentatively biodegraded with Brevibacillus brevis. A probable degradation pathway was further proposed with the cellular reactions discussed in detail. Experiments showed that B. brevis at 2 g L−1 could degrade 1 mg L−1 tri-m-cresyl phosphate, tri-p-cresyl phosphate, and tri-o-cresyl phosphate by 82.91%, 93.91%, and 53.92%, respectively, within five days. In the process of biodegradation, B. brevis metabolism caused the release of Na+ and Cl− as well as the absorption of some nutrient ions including K+, PO43−, Mg2+, and SO42−; the presence of oxalic acid, citric acid, acetic acid, and malonic acid was also detected. Similar metabolic pathways were found among different TCPs isomers, but tri-o-cresyl phosphate induced more reactive oxygen species than the other two did. This work develops novel insights into the potential mechanisms of TCPs biodegradation by microorganisms.
Agid:
6454396