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Changes in lipid classes of Drosophila melanogaster in response to selection for three stress traits

Author:
Ko, Li, Harshman, Lawrence, Hangartner, Sandra, Hoffmann, Ary, Kachman, Steve, Black, Paul
Source:
Journal of insect physiology 2019 v.117 pp. 103890
ISSN:
0022-1910
Subject:
Drosophila melanogaster, acids, cold, diacylglycerols, heat, heat shock response, insect physiology, pesticide resistance, triacylglycerols
Abstract:
Laboratory selection on environmental stress traits is an evolutionary approach that is informative in the context of understanding stress adaptation. Here we characterize changes in a lipidome of Drosophila melanogaster in lines selected for increased heat (elevated heat knockdown refractoriness), cold (decreased time to recover from chill-coma) and desiccation survival. Selection for desiccation resistance resulted in changes in multiple lipid classes used to characterize a lipidome. This included a decrease in triacylglycerols (TAGs) which is relevant to interpretation of storage lipid levels in previous D. melanogaster desiccation survival selection experiments. Chill-coma recovery rate selection was expected to show extensive changes in lipid classes, but only phosphatidic acids exhibited significant change. Selection for increased heat knockdown resistance resulted in a substantial change in the abundance of a class of lipids (diacylglycerols) which could play a role in mediating the heat shock response or result in an increase in neutral lipid mobilization.
Agid:
6457330