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Effects of beeswax-carboxymethyl cellulose composite coating on shelf-life stability and intestinal delivery of holy basil essential oil-loaded gelatin microcapsules

Ngamekaue, Narisara, Chitprasert, Pakamon
International journal of biological macromolecules 2019 v.135 pp. 1088-1097
Ocimum tenuiflorum, antibacterial properties, antioxidant activity, beeswax, carboxymethylcellulose, coatings, essential oils, feed additives, gastric juice, gelatin, lipid content, microencapsulation, oils, shelf life, small intestine
Despite growing interests in the use of essential oils in food and feed additives to promote health benefits, several studies have indicated that microencapsulation of these sensitive materials is necessary to increase their stability and improve their release profiles. This study aimed to investigate the effects of emulsion-based composite from beeswax (1, 2, and 3%) and carboxymethyl cellulose (CMC) for coating on the stability and delivery of holy basil essential oil-loaded gelatin microcapsules (HBEO-G) prepared by simple coacervation. After 3-month storage, the highest surface oil content was observed in HBEO-G, followed by the 3, 1, and 2% beeswax-CMC coated microcapsules. The antioxidant activity of only the 2% beeswax-CMC coated microcapsule (2B-HBEO-G) remained constant, whereas the antibacterial activities of all microcapsules did not significantly change over time. 2B-HBEO-G minimized exposure of the loaded HBEO in the simulated gastric fluids and delivered the oil to the distal small intestine.