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Disease control of Phytophthora infestans using cyazofamid encapsulated in poly lactic-co-glycolic acid (PLGA) nanoparticles

Author:
Fukamachi, Kazuto, Konishi, Yasuhiro, Nomura, Toshiyuki
Source:
Colloids and surfaces 2019
ISSN:
0927-7757
Subject:
Phytophthora infestans, adhesion, antimicrobial properties, biodegradability, cyazofamid, disease control, encapsulation, food production, fungal diseases of plants, leaves, nanoparticles, pest control, plant pathogenic fungi, polymers, rain, scanning electron microscopy, sporangia, thermodynamics, tomatoes, zoospores
Abstract:
Pesticides are widely used in food production to control pests. However, less than 0.1% of pesticides reach their biological targets. The concept of a “Pesticide Delivery System” may solve various problems related to pesticides in agriculture. The aim of this study was to control the disease caused by Phytophthora infestans using cyazofamid encapsulated in biodegradable poly lactic-co-glycolic acid (PLGA) nanoparticles (NPs). As a result, PLGA NPs were taken into sporangia, encysted zoospores and germinated cysts of P. infestans. In an in vitro antimicrobial activity assay, cyazofamid encapsulated in PLGA NPs obviously inhibited zoospore release from sporangia. In an in vivo rainfastness test, P. infestans infection of tomato leaves was suppressed by cyazofamid encapsulated in PLGA NPs. In addition, the PLGA NPs had thermodynamically favorable properties for stable adhesion to tomato leaves and SEM observation revealed that the NPs remained on the leaf after artificial rainfall. In conclusion, this study suggests that encapsulating pesticides in biodegradable polymer NPs is an effective pesticide delivery system and could be a breakthrough load reduction technique in agriculture.
Agid:
6462142