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A general and practical Ni-catalyzed C–H perfluoroalkylation of (hetero)arenes
- Zhang, Shaoke, Rotta-Loria, Nicolas, Weniger, Florian, Rabeah, Jabor, Neumann, Helfried, Taeschler, Christoph, Beller, Matthias
- Chemical communications 2019 v.55 no.47 pp. 6723-6726
- air, aldehydes, aromatic hydrocarbons, chemical reactions, moieties, nickel
- A direct perfluoroalkylation of (hetero)arenes using the air- and moisture-stable complex (dppf)Ni(o-tol)Cl was developed (23 examples). The novel procedure allows for the synthesis of various fluorinated products and tolerates sensitive functional groups including aldehydes, free amino groups and several heterocycles.