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Chemical identification and antimicrobial potential of essential oil of Piper rivinoides kunth (BETIS-WHITE)

Author:
Alves Borges Leal, Antonio Linkoln, Machado, Antonio Judson Targino, Bezerra, Camila Fonseca, Serra Inácio, Cicero Emerson, Rocha, Janaína Esmeraldo, Sales, Débora Lima, de Freitas, Thiago Sampaio, de Oliveira Almeida, Waltécio, Amaral, Wanderlei do, Everson da Silva, Luiz, Ferriani, Aurea Portes, de Noronha Sales Maia, Beatriz Helena Lameiro, Bezerra Morais-Braga, Maria Flaviana, Barreto, Humberto Medeiros, Coutinho, Henrique Douglas Melo
Source:
Food and chemical toxicology 2019 v.131 pp. 110559
ISSN:
0278-6915
Subject:
Candida albicans, Candida tropicalis, Escherichia coli, Piper, Staphylococcus aureus, antagonism, antifungal properties, bacteria, chemical composition, erythromycin, essential oils, flame ionization, fungi, gentamicin, norfloxacin, petroleum, synergism, toxicology
Abstract:
The family Piperaceae is known for presenting in its species flavoring, healing and antimicrobial properties among others. The objective of the present study was: to study the chemical profile of the essential oil of Piper rivinoides (EOPR); to analyze its anti-bacterial and antifungal potential, as well as to evaluate the antifungal and antibiotic-modifying capacity. The chemical constituents were identified by gas chromatography with flame ionization detector (GC-FID), allowing the identification of 7 constituents of a total of 86.99%. E-Isoelemicin was identified as the main constituent of petroleum (40.81%). Clinically relevant MIC results were obtained against fungi in which the inhibitory concentration remained <256 μg/mL, as for Candida albicans 4127 (217.6 μg/mL). The association of EOPR with an antifungal showed a high synergistic affinity against the strains of C. tropicalis 40042 and 4262. We concluded that no intrinsic EOPR activity was observed at any concentrations tested against bacteria. However, EOPR associated with Gentamicin acted synergistically against S. aureus 10 and Escherichia coli 06, but with Erythromycin there was a synergistic effect against Escherichia coli 06, and antagonism with norfloxacin.
Agid:
6466452