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Allylation of aldehydes by dual photoredox and nickel catalysis
- Gualandi, Andrea, Rodeghiero, Giacomo, Faraone, Adriana, Patuzzo, Filippo, Marchini, Marianna, Calogero, Francesco, Perciaccante, Rossana, Jansen, Thomas Paul, Ceroni, Paola, Cozzi, Pier Giorgio
- Chemical communications 2019 v.55 no.48 pp. 6838-6841
- alcohols, aldehydes, allylation, catalysts, catalytic activity, heterocyclic compounds, irradiation, nickel, redox reactions, ruthenium
- Here we report the application of dual nickel/photoredox catalysis to the allylation of aliphatic, aromatic and heteroaromatic aldehydes by using commercially available reagents. The process utilizes the combination of a Ni(ii) complex, [Ru(bpy)₃]²⁺ as a photoredox catalyst, and allylacetate under blue LED irradiation, and allows the synthesis of a large variety of homoallylic alcohols.