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Hollow copper sulfide nanocubes as multifunctional nanozymes for colorimetric detection of dopamine and electrochemical detection of glucose

Author:
Zhu, Junlun, Peng, Xu, Nie, Wei, Wang, Yijia, Gao, Jingwen, Wen, Wei, Selvaraj, Jonathan Nimal, Zhang, Xiuhua, Wang, Shengfu
Source:
Biosensors & bioelectronics 2019 v.141 pp. 111450
ISSN:
0956-5663
Subject:
biosensors, catalysts, catalytic activity, chemiluminescence, colorimetry, dopamine, electrochemistry, glucose, hydrogen peroxide, lighting, nanomaterials, near infrared radiation, neoplasms, oxidation, prototypes, surface area, therapeutics
Abstract:
Nanozymes have fascinated increasing attention in the field of artificial enzyme. Designing an ideal nanozyme usually requires a synergic advantage of reasonable nanostructures and large specific surface area for ensuring excellent mimicking-enzyme catalytic activity. Here we report a CuS nanozyme with hollow nanocube structure (h-CuS NCs), which has a large surface area of 57.84 m2 g−1, and thus realizes excellent mimicking-enzyme catalytic activity. Expectedly, our directed design of h-CuS NCs nanozymes has an affinity for H2O2 of 0.94 mM, which is outstanding among the state-of-the-art Cu-based nanozymes. Furthermore, this nanozyme acts as a multifunctional catalyst to induce luminol chemiluminescence and oxide 3, 3′, 5, 5′-tetramethylbenzidine (TMB) in the presence of H2O2, and displays distinguished electrocatalytic activity to glucose oxidation. More intriguingly, the nanozyme can produce a promising photothermal effect under the illumination of near-infrared light. This work will provide a prototype for rational design of distinct nanostructures as multifunctional nanozymes in the area of electrochemical sensing, mimicking-enzyme catalytic biosening and cancer therapy.
Agid:
6484314