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Healthy Lifestyle and Incidence of Metabolic Syndrome in the SUN Cohort

Author:
Maria Garralda-Del-Villar, Silvia Carlos-Chillerón, Jesus Diaz-Gutierrez, Miguel Ruiz-Canela, Alfredo Gea, Miguel Angel Martínez-González, Maira Bes-Rastrollo, Liz Ruiz-Estigarribia, Stefanos N. Kales, Alejandro Fernández-Montero
Source:
Nutrients 2018 v.11 no.1 pp. -
ISSN:
2072-6643
Subject:
Mediterranean diet, alcohol drinking, alcoholic beverages, binging, chronic diseases, cohort studies, confidence interval, health promotion, lifestyle, men, metabolic syndrome, odds ratio, physical activity, risk reduction, television, women
Abstract:
We assessed the relationship between a healthy lifestyle and the subsequent risk of developing metabolic syndrome. The &ldquo;Seguimiento Universidad de Navarra&rdquo; (SUN) Project is a prospective cohort study, focused on nutrition, lifestyle, and chronic diseases. Participants (n = 10,807, mean age 37 years, 67% women) initially free of metabolic syndrome were followed prospectively for a minimum of 6 years. To evaluate healthy lifestyle, nine habits were used to derive a Healthy Lifestyle Score (HLS): Never smoking, moderate to high physical activity (>20 MET-h/week), Mediterranean diet (&ge;4/8 adherence points), moderate alcohol consumption (women, 0.1&ndash;5.0 g/day; men, 0.1&ndash;10.0 g/day), low television exposure (<2 h/day), no binge drinking (&le;5 alcoholic drinks at any time), taking a short afternoon nap (<30 min/day), meeting up with friends >1 h/day, and working at least 40 h/week. Metabolic syndrome was defined according to the harmonizing definition. The association between the baseline HLS and metabolic syndrome at follow-up was assessed with multivariable-adjusted logistic regressions. During follow-up, we observed 458 (4.24%) new cases of metabolic syndrome. Participants in the highest category of HLS adherence (7&ndash;9 points) enjoyed a significantly reduced risk of developing metabolic syndrome compared to those in the lowest category (0&ndash;3 points) (adjusted odds ratio (OR) = 0.66, 95% confidence interval (CI) = 0.47&ndash;0.93). Higher adherence to the Healthy Lifestyle Score was associated with a lower risk of developing metabolic syndrome. The HLS may be a simple metabolic health promotion tool.
Agid:
6506782